Pope Benedict XVI appealed for peace in trouble spots like Tibet, Iraq and the Holy Land during his Easter Sunday address.
The Pope also mentioned Darfur and Somalia during his appearance at Vatican City's St. Peter's Square.
He encouraged the world to seek solutions that will safeguard peace and the common good.
Injustice, hatred and violence between both individuals and peoples were all denounced by the Pope in his twice-yearly "Urbi et Orbi" (to the city and the world) blessing and message.
Pope Benedict delivered Easter greetings in 63 languages.
Tens of thousands of pilgrims had to huddle under umbrellas as wind-driven rain whipped the plaza.
At a Saturday night Easter vigil mass, the Pope baptized Magdi Allam. The Muslim-born convert is a strong critic of Islamic extremism and an outspoken defender of Israel.
Popes traditionally christen adult converts to Catholicism on Easter eve.
Police protect Allam with an escort because of the threats he has received.
In recent days, al Qaeda leader Osama bin Laden accused the Pope of support a "new Crusade" against Muslims. However, no security incidents were reported Sunday.
The Holy Land
In Israel, pilgrims braved a heat wave to flock to sites sacred to Christianity.
In the walled Old City of Jerusalem, they went to the Holy Sepulchre, which sits on the site where Jesus was crucified, buried and resurrected about two millenia ago.
Some Protestants gathered outside the city at the Garden Tomb, believed by some to be the site of Jesus's burial.
This time also coincides with the Jewish festival of Purim, which is a celebration of Jewish deliverance.
Security was high because of fears about a possible revenge attack by Hezbollah in connection with the assassination of a Hezbollah commander in February.
With files from The Associated Press