Skyrocketing U.S. insulin prices are driving a caravan of Americans with diabetes to the Canadian birthplace of the life-saving medication.

Organizer and diabetes advocate Quinn Nystrom said up to 45 people with Type 1 diabetes are expected to make the weekend trip to London, Ont., by bus or car from different U.S. cities.

鈥淭his is a crisis of epic proportions here in America. People are desperate and people are dying because they can鈥檛 afford insulin,鈥� she told CTVNews.ca in a telephone interview, before her 25-person group from Minneapolis, Minn. left Friday.

U.S. insulin prices have soared over the past two decades. An American Diabetes Association spokesperson told CTVNews.ca the average price of insulin has nearly tripled between 2002 and 2013.

When Nystrom was diagnosed 20 years ago, she said insulin was around US$16 per vial. Now, it costs her US$340 -- roughly 10 times the price in Canada.

The Minnesotan caravan, which is being joined by people in Illinois and Michigan, is visiting Banting House in London, Ont., where Sir Frederick Banting came up with his idea that led to the discovery of insulin 99 years ago.

The group will hold a news conference on Saturday, joined by nearly two dozen U.S. media outlets also making the trip.

Banting famously he believed his discovery belonged to the world and not for profit.

Caravan member Deb Souther told CTVNews.ca over the phone that to people with diabetes, Banting is 鈥渁lmost like our patron saint.鈥�


CANADIAN PRICES APPROXIMATELY 1/10 OF U.S. PRICES

This marks the core group鈥檚 second trip to Canada to buy significantly cheaper insulin, which people with diabetes use to regulate their blood glucose levels.

In early May, the group of only six Minnesotans -- including parents going on their children鈥檚 behalf -- drove 1,000 km to a Shoppers Drug Mart in Fort Frances, Ont.

Amie Criego from East Lansing, Mich. has gone on stretches in the past without health insurance. During those times, she recalls asking friends for insulin because she couldn鈥檛 afford it.

鈥淚 mean it鈥檚 bad and upsetting that (this) is necessary,鈥� Criego told CTVNews.ca in a telephone interview. Although this is the first time she鈥檚 made the trip, she said it 鈥減robably'' won't be the last.

She admits that she 鈥渉ad no idea how much insulin costed鈥� before she was diagnosed.

Canadian insulin prices can be approximately a tenth of those in the U.S. When Nystrom crossed the border the first time, she ended up paying US$300 for insulin, which would have cost US$3,300 stateside.

Fellow traveller Souther, who was diagnosed more than 45 years ago, uses three vials of insulin that each cost US$380 each month. In Canada, each vial is under US$40.

Souther said she鈥檚 now waiting for her husband鈥檚 insurance from his new job to kick in.

鈥淭his can鈥檛 keep going on,鈥� she said. 鈥淭here鈥檚 a lot of people who can鈥檛 make it to Canada and they鈥檙e actually losing their lives 鈥� and having to ration their insulin.鈥�


UNLIKE U.S., CANADA鈥橲 SYSTEM REDUCES PRICE GOUGING

The reason for the discrepancy is because Canada regulates drug prices through the quasi-judicial Patented Medicine Prices Review Board designed to prevent gouging.

In the U.S., market forces are the lay of the land. But Nystrom said this needs to change for the sake of her and people affected by crippling drug prices.

While four states including Florida have passed legislation allowing for wholesale or individual imports of medications, advocates like Nystrom say it won鈥檛 be enough until there鈥檚 a plan for the entire country.

All the current U.S. medical tourists acknowledge that trips like this aren鈥檛 a long-term solution.

But in the short-term, Barry Power, a senior director with the Canadian Pharmacists Association, said he was concerned despite the group鈥檚 relatively small scale.

"Any time you have a large population such as the U.S ... coming to Canada to access medications that are earmarked for the Canadian market, there's potential for disruption of some sort,鈥� he told The Canadian Press.

With files from The Canadian Press