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Health Canada sticks with Evusheld despite U.S. FDA dropping the COVID drug

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While Health Canada says it is "aware" of the U.S. decision to withdraw the emergency use of Evusheld, a drug by AstraZeneca used to help prevent COVID-19 infection--- the agency is maintaining its approval, citing the differences in variant circulation between Canada and the U.S.

that its emergency use authorization of the drug was pulled due to its inefficacy in treating 鈥渃ertain鈥 COVID-19 variants.

The FDA stated in a release on its website that as the XBB.1.5. variant, nicknamed 鈥淜raken鈥, is making up the majority of cases in the country, the use of Evusheld is 鈥渘ot expected to provide protection鈥 and therefore not worth exposing the public to possible side effects of the drug, like allergic reactions.

In an email to CTVNews.ca, Health Canada said the U.S. Food and Drug Administration pulled the drug as the main variant of concern in the U.S. is XBB.1.5.

"Dominant variants in the [U.S.] may be different from those circulating in Canada," the federal agency said in an email. "The most recent epidemiological data in Canada (as of January 1, 2023) indicate that BA.5 (Omicron) subvariants continue to account for more than 89 per cent of reported cases."

that certain variants are not neutralized by Evusheld and cautioned people who are exposed to XBB.1.5. On Jan. 26, the FDA then updated its website by saying it would be limiting the use of Evusheld.

"Evusheld is not currently authorized for use in the U.S. until further notice by the Agency," the FDA website states.

On Jan. 17, , explaining how it may not be effective against certain Omicron subvariants when used as a preventative measure or treatment for COVID-19.

"Decisions regarding the use of EVUSHELD should take into consideration what is known about the characteristics of the circulating COVID-19 variants, including geographical prevalence and individual exposure," Health Canada said in an email.

Health Canada says Evusheld , which according to the agency, is the dominant variant in many communities in Canada.

The drug was introduced for and are unlikely to be protected by a COVID-19 vaccine. It can only be given to people 12 years and older.

"EVUSHELD is not a substitute for vaccination in individuals for whom COVID-19 vaccination is recommended," the agency's website reads.

Health Canada says no drug, including Evusheld, is a substitute for vaccination.

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