鶹Ӱ

Health

    • Canadian university researchers find 'most effective' treatment for excessive daytime sleepiness

    Two researchers from McMaster University have found what they call the ‘most effective’ treatment for excessive daytime sleepiness, which is commonly caused by obstructive sleep apnea.(Photo: pexels) Two researchers from McMaster University have found what they call the ‘most effective’ treatment for excessive daytime sleepiness, which is commonly caused by obstructive sleep apnea.(Photo: pexels)
    Share

    Researchers from McMaster University have what they call the “most effective” treatment for people with obstructive sleep apnea (OSA) who suffer from excessive daytime sleepiness (EDS).

    Dena Zeraatkar and Tyler Pitre published their results in the peer-reviewed publication Annals of Internal Medicine, claiming the drug solriamfetol is “likely the best medication” for EDS.

    Their findings are based on a systematic review of 14 clinical trials of anti-fatigue medications involving 3,085 people, as well as analysing data from MEDLINE, CENTRAL, EMBASE and ClinicalTrials.gov in a specific network meta-analysis.

    Their research was conducted from October 2022 to January 2023.

    EDS is when someone falls asleep or has a desire for sleep while expected to be awake, and it is often a symptom of sleep-related disorders.

    The standard treatment for OSA is a positive airway pressure (PAP) mask that uses compressed air to support lung airways during sleep. However, some people with OSA still experience EDS and may benefit from anti-fatigue medication.

    Tyler Pitre, study author and resident physician in internal medicine at McMaster University and incoming respirology fellow at the University of Toronto, suggests people with OSA should use their PAP machine first to treat EDS, and if they are still sleepy they can turn to medication for treatment.

    “Fifteen to 30 per cent of people in North America have a diagnosis of OSA and the prevalence could be much higher as many others are undiagnosed. Many people have symptoms as the condition is highly associated with obesity, which affects a large and increasing number of people in Canada, the United States and other high-income countries,” added Pitre. “Among those patients, many will have EDS, which affects their quality of life, making them less productive and also puts them at risk of other psychological issues. Improving this situation is of paramount importance to physicians.”

    According to Pitre, OSA affects nearly one billion people in the world and puts many of them at risk of EDS.

    While the study determined solriamfetol is “likely the best” anti-fatigue drug for EDS, senior study author and an assistant professor of the Department of Anesthesia Zeraatkar says the drugs armodafinil–modafinil and pitolisant are also effective in combating fatigue.

    Zeraatkar also says solriamfetol can raise blood pressure and it may be risky for people with OSA, as many of them also have cardiovascular issues.

    “It would be interesting to see how effective these anti-fatigue medications will be for treating related illnesses such as chronic fatigue syndrome and long COVID, now that we know they work for a similar condition,” added Zeraatkar.

     

    Reporting for this story was paid for through The Afghan Journalists in Residence Project funded by Meta.

    CTVNews.ca Top Stories

    Three men were injured after trying to subdue a man armed with a knife during afternoon prayers at a Montreal-area mosque Friday afternoon.

    Unusual flippered feet are making their way into the Saint Lawrence River this weekend. Led by underwater explorer and filmmaker Nathalie Lasselin, volunteer divers are combing the riverbed near Beauharnois in Montérégie to remove hundreds of tires that have been polluting the aquatic environment for decades.

    Canada

    • A man is facing numerous drug trafficking charges after Dufferin OPP seized a large assortment of drugs and weapons in Orangeville earlier this week.

    • The London Police Service (LPS) is currently investigating a suspicious death in the east end.

    • Unusual flippered feet are making their way into the Saint Lawrence River this weekend. Led by underwater explorer and filmmaker Nathalie Lasselin, volunteer divers are combing the riverbed near Beauharnois in Montérégie to remove hundreds of tires that have been polluting the aquatic environment for decades.

    • The 75-year-old building, formerly the Waskesiu Chamber of Commerce building, was relocated to the Parks Canada compound on the edge of the townsite.

    • Mattea Roach among the Maritimers honoured with the King Charles III Coronation Medal Friday.

    • Montrealers can get used to taking a stroll on several car-free streets during the summer in the years to come thanks to a new commitment from the city.

    World

    Politics

    Health

    Sci-Tech

    Entertainment

    Business

    Lifestyle

    • Tattoos are becoming more common in today's society and, as a result, appear to be more acceptable in the workplace than they used to be.

    • How to win the fight with kids over phone use

      The end of the day — when school, extracurricular activities and homework are (hopefully) finally done — is the window that many kids have for downtime. It can be a struggle to convince them not to go on their phones.

    • While slang may come and go, experts say the phenomenon behind them, which constantly churns out brand-new bon mots, is as old as language itself.

    Sports

    • Kiefer Sherwood spent several nights last spring chasing Quinn Hughes around the ice and generally pestering the Vancouver Canucks.

    • Cole Haas is more than just an avid fan of the F.W. Johnson Wildcats football team. He's a fixture on the sidelines, a source of encouragement, and a beloved member of the team.

    Autos

    Local Spotlight

    Cole Haas is more than just an avid fan of the F.W. Johnson Wildcats football team. He's a fixture on the sidelines, a source of encouragement, and a beloved member of the team.

    Getting a photograph of a rainbow? Common. Getting a photo of a lightning strike? Rare. Getting a photo of both at the same time? Extremely rare, but it happened to a Manitoba photographer this week.

    An anonymous business owner paid off the mortgage for a New Brunswick not-for-profit.

    They say a dog is a man’s best friend. In the case of Darren Cropper, from Bonfield, Ont., his three-year-old Siberian husky and golden retriever mix named Bear literally saved his life.

    A growing group of brides and wedding photographers from across the province say they have been taken for tens of thousands of dollars by a Barrie, Ont. wedding photographer.

    Paleontologists from the Royal B.C. Museum have uncovered "a trove of extraordinary fossils" high in the mountains of northern B.C., the museum announced Thursday.

    The search for a missing ancient 28-year-old chocolate donkey ended with a tragic discovery Wednesday.

    The Royal Canadian Mounted Police is celebrating an important milestone in the organization's history: 50 years since the first women joined the force.

    It's been a whirlwind of joyful events for a northern Ontario couple who just welcomed a baby into their family and won the $70 million Lotto Max jackpot last month.

    • A six-year-old girl who was reported missing in northern B.C. earlier this week remains unaccounted for, and "significant resources from across the province" have joined in the search, police said Saturday.

    • A man who was found dead behind a curling rink in Nanaimo, B.C., earlier this month was the victim of a homicide, police confirmed.

    • No one was injured when a large fire destroyed a home in a rural part of Surrey overnight.

    • A suspect wanted in a homicide in Richmond Hill has been arrested, York Regional Police say.

    • Toronto police say they have now identified a third person who they believe was involved in a shooting that left two men dead in North York earlier this week.

    • A man is fighting for his life in hospital a day after a vehicle smashed into several others in and around an intersection in Milton before flipping over.

    • The water coming from your taps might be a bit murky Saturday, but Calgary remains on schedule to end all water restrictions on Sunday.

    • An estimated 8,000 volunteers mobilized across the city Saturday as the Calgary Food Bank went door-to-door collecting food and funds.

    • The man charged with fatally stabbing lifelong Banff resident Ethan Enns-Goneau in 2022 has been convicted of second-degree murder.

    • A woman who went missing on the Ottawa River near Pembroke, Ont. while kayaking Tuesday night has been found dead, according to the Ontario Provincial Police (OPP).

    • A joint police operation to promote safe driving on Highway 417 in the Ottawa area has resulted in laying dozens of charges in three hours Friday, according to the Ontario Provincial Police (OPP).

    • Whether it was a big truck, or a small one, the construction trucks rolling past the Children’s Hospital of Eastern Ontario (CHEO) on Saturday had a very important job, and it's putting smiles on the faces of little ones.

    • Montrealers can get used to taking a stroll on several car-free streets during the summer in the years to come thanks to a new commitment from the city.

    • Three men were injured after trying to subdue a man armed with a knife during afternoon prayers at a Montreal-area mosque Friday afternoon.

    • Unusual flippered feet are making their way into the Saint Lawrence River this weekend. Led by underwater explorer and filmmaker Nathalie Lasselin, volunteer divers are combing the riverbed near Beauharnois in Montérégie to remove hundreds of tires that have been polluting the aquatic environment for decades.

    • Tattoos are becoming more common in today's society and, as a result, appear to be more acceptable in the workplace than they used to be.

    • The Edmonton Police Service is looking for a person of interest in connection with a suspicious fire that destroyed a multi-unit building and damaged several townhomes earlier this week.

    • Former Edmonton Oiler Zack Kassian has rejoined the team as a pro scout, the Oilers announced on Saturday.

    • Halifax Regional Police warned the public of a series of high-value thefts targeting retail stores Friday.

    • Pictou County District RCMP is investigating a fatal crash that occurred in Thorburn, N.S., Saturday.

    • A proposal for additional parking to accommodate upgrades at the Irving Pulp & Paper Mill in Saint John, N.B., would add an estimated 500 parking spots at Wolastoq Park.

    • The search for a missing six-year-old boy in Shamattawa is continuing Friday as RCMP hope recent tips can help lead to a happy conclusion.

    • A herd of dogs paid visit to patients and residents at Riverview Health Centre during an annual event that lifts spirits and wags tails.

    • While slang may come and go, experts say the phenomenon behind them, which constantly churns out brand-new bon mots, is as old as language itself.

    • The last two months after losing her daughter Bella have been extremely difficult for Kyla Thomson.

    • Regina police arrested three youths in connection to a bear mace incident at a Regina high school on Friday.

    • Heading into Friday's game against the Calgary Stampeders, quarterback Trevor Harris said he and his Saskatchewan Roughriders were "ready to rock."

    • The Cambridge Professional Fire Fighters’ Association held their annual Muscular Dystrophy Boot Drive on Saturday.

    • Protests were held in front of Kitchener City Hall on Friday, both for and against LGBTQ2S+ inclusive education and queer rights in schools.

    • The provincial government is considering new rules to restrict a municipality’s ability to install new bike lanes if it means traffic lanes would be removed.

    • Heading into Friday's game against the Calgary Stampeders, quarterback Trevor Harris said he and his Saskatchewan Roughriders were "ready to rock."

    • The City of Saskatoon is proposing changes to the proposed downtown shelter site plan following feedback from nearby residents and businesses.

    • The 75-year-old building, formerly the Waskesiu Chamber of Commerce building, was relocated to the Parks Canada compound on the edge of the townsite.

    • A motorcyclist has died following a serious collision that took place in London’s south end on Friday afternoon.

    • The London Police Service (LPS) is currently investigating a suspicious death in the east end.

    • The St. Thomas police is asking the public for help locating a missing man.

    • A man is facing numerous drug trafficking charges after Dufferin OPP seized a large assortment of drugs and weapons in Orangeville earlier this week.

    • One person is in hospital after an e-bike crash in Orillia on Thursday.

    • On Saturday, OPP officers responded to a call after a car hit a tree in a parking lot at 8:00 a.m. on West St. S and King St in Orillia.

    • The Amherstburg Freedom Museum is celebrating a year of festivities in anticipation of its 50th anniversary in 2025.

    • The St. Clair College golf teams were successful at the Niagara Knights Invitational tournament on Friday.

    • A LaSalle high school is celebrating its emerald anniversary this weekend, with everyone who has ever walked its halls invited to return.

    • A man who was found dead behind a curling rink in Nanaimo, B.C., earlier this month was the victim of a homicide, police confirmed.

    • A six-year-old girl who was reported missing in northern B.C. earlier this week remains unaccounted for, and "significant resources from across the province" have joined in the search, police said Saturday.

    • The British Columbia election campaign is set to officially start today, with Lt.-Gov. Janet Austin issuing the writ for the Oct. 19 vote.

    • A pair of runaway pigs are in the custody of an animal sanctuary in the Okanagan after evading police and volunteers for hours earlier this week.

    • The Red Bridge, a historic landmark in Kamloops, B.C., was completely destroyed by fire early Thursday morning.

    • Animal protection officers in British Columbia have rescued three pit bulls – including one that gave birth to 10 puppies – from a rat-infested home in Kelowna.

    • Despite the heavy rain, plenty of muscle turned up for United Way’s annual Pull the Bus fundraiser in Lethbridge Friday.

    • Lethbridge County has rescinded its fire restriction as a result of the recent cool, wet weathr.

    • The Lethbridge Hurricanes kicked off the 2024-25 season on a winning note Friday night, defeating the Edmonton Oil Kings 3-1 in a game played at VisitLethbridge.com Arena.

    • Following an outbreak of COVID-19 on its continuing care floor and just ahead of the flu season, St. Joseph’s General Hospital in Elliot Lake has opted to re-introduce a universal masking policy until further notice.

    • A 26-year-old driver from Surrey, B.C., has been charged with three counts of criminal negligence causing death and bodily harm in a crash that killed two youths in northern Ontario last year.

    • Ontario Provincial Police say three suspects from southern Ontario have been charged and drugs worth $300,000 have been seized following a traffic stop Sept. 16.

    N.L.

    Shopping Trends

    The Shopping Trends team is independent of the journalists at 鶹Ӱ. We may earn a commission when you use our links to shop. Read about us.

    Stay Connected
    Follow 鶹Ӱ